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PRotein Ontology (PRO) Release 9.0, version 0
05-March-2010

The Protein Ontology Consortium--Protein Information Resource, The Jackson Laboratory, Reactome, and the Department of Philosophy at the
State University of New York at Buffalo--is pleased to announce PRO Release 9.0 (05-March-2010). PRO describes the relationships of proteins and protein evolutionary classes, delineates the multiple protein forms of a gene locus (ontology for protein forms), and interconnects existing ontologies. Further information is available at http://pir.georgetown.edu/pro/.

In PRO Release 9.0, version 0:

There are 24794 PRO terms
   5363 terms are in the 'modification' category.
   965 terms are in the 'sequence' category.
   18159 terms are in the 'gene' category.
   270 terms are in the 'family' category.
1257 terms have some kind of annotation, codifying the information from 890 papers.
  1869 connections to GO (623 PRO terms).
  236 connections to MOD (195 PRO terms).
  599 connections to Pfam (358 PRO terms).
  325 connections to SO (307 PRO terms).
  296 annotations of a phenotype (289 PRO terms).


The ontology includes a subset of terms from MOD, MI, and SO ontologies that are used for logical definitions.  If using OBO Edit to view PRO, please turn on the reasoner in order to display the hierarchy.

_Changes from Release 8.0_

We have added a new node for proteolytic cleavage products, which are derived_from proteins.  This node will facilitate the creation of
logical definitions.  As a result, we have created a new root node for both, "amino acid chain."  This new root node will also allow the future inclusion of peptides created de novo (non-ribosomally).

We have added terms based on the Escherichia coli proteome.
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