PRotein Ontology (PRO) Release 52.0, version 0
07-Apr-2017

The Protein Ontology Consortium--Protein Information Resource, The Jackson Laboratory, Reactome, and the Department of Philosophy at the State University of New York at Buffalo--is pleased to announce PRO Release 51.0 (23-Dec-2016). PRO describes the relationships of proteins and protein evolutionary classes, delineates the multiple protein forms of a gene locus (ontology for protein forms), protein complexes, and interconnects existing ontologies. Further information is available at http://www.proteininformationresource.org/pro/.

In PRO Release 52.0, version 0:
There are 213457 PRO terms in the Protein Ontology. Those representing individual proteins are mapped to 130442 UniProtKB sequences.
      59 terms are in the 'external' category.
      83 terms are in the 'organism-seqgroup' category.
     404 terms are in the 'family' category.
   23571 terms are in the 'gene' category.
    8331 terms are in the 'sequence' category.
    6678 terms are in the 'modification' category.
     212 terms are in the 'complex' category.
      34 terms are in the 'organism-family' category.
   97147 terms are in the 'organism-gene' category.
   69524 terms are in the 'organism-sequence' category.
    6462 terms are in the 'organism-modification' category.
     385 terms are in the 'organism-complex' category.
     121 terms are in the 'union' category.
2514 terms have some kind of annotation, codifying the information from 1674 papers.
    4419 connections to GO (1711 PRO terms).
     292 connections to MOD (255 PRO terms).
     616 connections to Pfam (369 PRO terms).
     338 connections to SO (317 PRO terms).
     349 annotations of a phenotype (342 PRO terms).

The ontology includes a subset of terms from GO, MOD, CHEBI, and SO ontologies that are used for logical definitions. 


_Current changes_

1) File changes: The redundant files pro.obo and pro.owl will no longer be distributed. 

Summary of the changes:

Previous releases:
pro_nonreasoned.obo = nonreasoned
pro_nonreasoned.owl = nonreasoned
pro_reasoned.obo = reasoned
pro_reasoned.owl = reasoned
pro.obo = nonreasoned (just an exact copy of the pro_reasoned.obo)
pro.owl = nonreasoned (just an exact copy of the pro_reasoned.owl)

Current release:
pro_nonreasoned.obo = nonreasoned
pro_nonreasoned.owl = nonreasoned
pro_reasoned.obo = reasoned
pro_reasoned.owl = reasoned

Note that the purls
  http://purl.obolibrary.org/obo/pr.obo
  http://purl.obolibrary.org/obo/pr.owl
link to the reasoned versions.

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