PRotein Ontology (PRO) Release 49.0, version 0
13-May-2016

The Protein Ontology Consortium--Protein Information Resource, The Jackson Laboratory, Reactome, and the Department of Philosophy at the State University of New York at Buffalo--is pleased to announce PRO Release 49.0 (13-May-2016). PRO describes the relationships of proteins and protein evolutionary classes, delineates the multiple protein forms of a gene locus (ontology for protein forms), protein complexes, and interconnects existing ontologies. Further information is available at http://www.proteininformationresource.org/pro/.

In PRO Release 49.0, version 0:
There are 203284 PRO terms in the Protein Ontology. Those representing individual proteins are mapped to 127370 UniProtKB sequences.
      57 terms are in the 'external' category.
     402 terms are in the 'family' category.
   23559 terms are in the 'gene' category.
    8322 terms are in the 'sequence' category.
    6676 terms are in the 'modification' category.
     212 terms are in the 'complex' category.
      34 terms are in the 'organism-family' category.
   92855 terms are in the 'organism-gene' category.
   68138 terms are in the 'organism-sequence' category.
    2233 terms are in the 'organism-modification' category.
     380 terms are in the 'organism-complex' category.
     118 terms are in the 'union' category.
2516 terms have some kind of annotation, codifying the information from 1672 papers.
    4415 connections to GO (1709 PRO terms).
     292 connections to MOD (255 PRO terms).
     620 connections to Pfam (373 PRO terms).
     338 connections to SO (317 PRO terms).
     349 annotations of a phenotype (342 PRO terms).

The ontology includes a subset of terms from GO, MOD, CHEBI, and SO ontologies that are used for logical definitions. If using OBO Edit to view PRO, please turn on the reasoner in order to display the hierarchy.

_Current changes_

None

_Forthcoming changes_

1) In Release 50 the default download version of PRO (http://purl.obolibrary.org/obo/pr.obo) will be the reasoned version (now called pro_reasoned.obo).

2) Continue to add shorthand labels to terms.

3) Resolve names and synonym duplicates.




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