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PRotein Ontology (PRO) Release 33.0, version 0
22-March-2013

The Protein Ontology Consortium--Protein Information Resource, The Jackson Laboratory, Reactome, and the Department of Philosophy at the State University of New York at Buffalo--is pleased to announce PRO Release 33.0 (22-March-2013). PRO describes the relationships of proteins and protein evolutionary classes, delineates the multiple protein forms of a gene locus (ontology for protein forms), protein complexes, and interconnects existing ontologies. Further information is available at http://pir.georgetown.edu/pro/.

In PRO Release 33.0, version 0:

There are 35287 PRO terms
     331 terms are in the 'family' category.
   23815 terms are in the 'gene' category.
    1657 terms are in the 'sequence' category.
    6492 terms are in the 'modification' category.
     136 terms are in the 'complex' category.
       4 terms are in the 'organism-family' category.
     934 terms are in the 'organism-gene' category.
     693 terms are in the 'organism-sequence' category.
     757 terms are in the 'organism-modification' category.
     260 terms are in the 'organism-complex' category.
      16 terms are in the 'union' category.
1801 terms have some kind of annotation, codifying the information from 1245 papers.
    2954 connections to GO (988 PRO terms).
     374 connections to MOD (328 PRO terms).
     610 connections to Pfam (365 PRO terms).
     338 connections to SO (317 PRO terms).
     344 annotations of a phenotype (337 PRO terms).


The ontology includes a subset of terms from GO, MOD, CHEBI, and SO ontologies that are used for logical definitions.  If using OBO Edit to view PRO, please turn on the reasoner in order to display the hierarchy.

_Current changes_

1) Please note that this release still contains a number of duplicate names and synonyms. These will be resolved in upcoming releases.

_Forthcoming changes_

1) Continue to add shorthand labels to terms.
2) Continue to expand the set of mapped terms.
3) Resolve names and synonym duplicates.

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