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PRotein Ontology (PRO) Release 16.0, version 0
25-February-2011

The Protein Ontology Consortium--Protein Information Resource, The Jackson Laboratory, Reactome, and the Department of Philosophy at the State University of New York at Buffalo--is pleased to announce PRO Release 16.0 (25-February-2011). PRO describes the relationships of proteins and protein evolutionary classes, delineates the multiple protein forms of a gene locus (ontology for protein forms), protein complexes, and interconnects existing ontologies. Further information is available at http://pir.georgetown.edu/pro/.

In PRO Release 16.0, version 0:

There are 26592 PRO terms
     304 terms are in the 'family' category.
   18200 terms are in the 'gene' category.
    1281 terms are in the 'sequence' category.
    5865 terms are in the 'modification' category.
      39 terms are in the 'complex' category.
     270 terms are in the 'organism-gene' category.
     280 terms are in the 'organism-sequence' category.
     155 terms are in the 'organism-modification' category.
      78 terms are in the 'organism-complex' category.
       8 terms are in the 'union' category.
1541 terms have some kind of annotation, codifying the information from 1027 papers.
    2271 connections to GO (770 PRO terms).
     374 connections to MOD (327 PRO terms).
     604 connections to Pfam (362 PRO terms).
     338 connections to SO (317 PRO terms).
     306 annotations of a phenotype (299 PRO terms).

The ontology includes a subset of terms from GO, MOD, CHEBI, and SO ontologies that are used for logical definitions.  If using OBO Edit to view PRO, please turn on the reasoner in order to display the hierarchy.

_Changes from Release 15.0_

1) PRO ID space changed from PRO: to PR: to avoid clashing with UniProtKB feature identifiers indicating processed protein subsequences (PRO_).
2) The document header tag "data-version" was added and includes the release information.

_Future changes_

3) From next release on we will no longer provide the ID space PRO: version of the files. 

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