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PRotein Ontology (PRO) Release 15.0, version 0
21-January-2011

The Protein Ontology Consortium--Protein Information Resource, The Jackson Laboratory, Reactome, and the Department of Philosophy at the State University of New York at Buffalo--is pleased to announce PRO Release 15.0 (21-January-2011). PRO describes the relationships of proteins and protein evolutionary classes, delineates the multiple protein forms of a gene locus (ontology for protein forms), protein complexes, and interconnects existing ontologies. Further information is available at http://pir.georgetown.edu/pro/.

In PRO Release 15.0, version 0:

There are 26167 PRO terms
     304 terms are in the 'family' category.
   18205 terms are in the 'gene' category.
    1235 terms are in the 'sequence' category.
    5705 terms are in the 'modification' category.
      35 terms are in the 'complex' category.
     178 terms are in the 'organism-gene' category.
     225 terms are in the 'organism-sequence' category.
     120 terms are in the 'organism-modification' category.
      49 terms are in the 'organism-complex' category.
       8 terms are in the 'union' category.
1515 terms have some kind of annotation, codifying the information from
                                                  976 papers.
    2133 connections to GO (744 PRO terms).
     374 connections to MOD (327 PRO terms).
     604 connections to Pfam (362 PRO terms).
     338 connections to SO (317 PRO terms).
     306 annotations of a phenotype (299 PRO terms).

The ontology includes a subset of terms from GO, MOD, CHEBI, and SO ontologies that are used for logical definitions.  If using OBO Edit to view PRO, please turn on the reasoner in order to display the hierarchy.

_Changes from Release 14.0_

1) PRO will supply a second file for each current file. The second file will contain a '_pr' (for example, pro_pr.obo or PAF_pr.txt) to indicate that the file uses the forthcoming PR: ID space (see below).

_Future changes_

1) PRO identifier will change from PRO: to PR:
Effective with next release "release 16.0" (barring unforeseen delays) the PRO ID space will change from PRO: to PR: to avoid clashing with UniProtKB feature identifiers indicating processed protein subsequences (PRO_).

2) In pro.obo, the "remarks" header tag will be removed and the release note will be added to the document header tag "data-version". 
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